Knights of Walpurgis

Archive for September, 2012|Monthly archive page

Antihypertensive Drugs

In Uncategorized on September 15, 2012 at 10:11 pm

Case I

Ben decided to go and enroll himself in a gym after his doctor diagnosed him with hypertension going into coronary heart disease. The doctor prescribed him with beta blockers so that he can exercise safely. It also solved his arrythmia.

Case II

Ren, Ben’s friend, also takes beta blockers because it reduces the release of renin from his juxtaglomerular apparatus. However, his doctor noticed that he is having prolonged time for high glucose content in the blood. Having antioxidant effects, it also made him feel younger. The doctor claimed that this would prevent him from having a myocardial infarction.

Case III

Bronco has asthma and hypertension. The doctor prescribed him some anti-hypertensive drugs except for beta blockers since these have bronchospasmic activity. He also has diabetes and this further eliminated beta blockers from the list of drugs. Being the badass he is, he still bought some beta blockers. He failed to have children. He was so sad and he thought it was because of his lack of children but it is actually an effect of the drug.

Case IV

Propio and Metong love eating salty food so much that they developed renal damage. They also have hypertension. As a doctor, you gave him propanolol and metroprolol. You also advised them to stick to their drug schedules or else, their blood pressure would shoot up and they would also have arrythmia. You also warned them about decreased desire for sexual intercourse.

Case V

Artemio and his bro, Narding went to you for check up. They are alcoholics and lab results have show that they have compromised livers. You decided to give them Atenolol and Nadolol for their high blood pressure.

 

Case VI

Prince has been diagnosed with vasospastic angina a.k.a. Prinzmetal variant angina. He was given calcium channel blockers. However, his condition progressed to chronic stable angina. After experiencing angina, his calcium channel medications were stopped and he was given beta adrenergic blockers and nitrates as replacement

 

Case VII

John Dillinger and his girlfriend, Vera Pam are hypertensive people due to all the car chases, bank robberies, armored car robberies and police and military police shootouts that they have been to. The doctor believes that a massive heart attack will happen to these two and decided not to give dihydropyridines. They were instead dosed with diltiazem (a benzothiazepine) and verapamil (a phenylalkylamine). Noted were facial swelling and constipation. Little does the doctor know that they are also taking other cardiac depressant and hypotensive drugs that resulted in addiction.

 

Case VIII

You want to increase the diameter of the coronary blood vessels of your patients, Nifemio and Nicardio. You given them Nifedipine and Nicardipine. You can also give them verapamil and diltiazem but these have longer lasting and more widespread effects. Their condition progressed to angina pectoris and you gave them nitrates and beta blockers. However, you returned them to using calcium channel blockers.

 

Case IX

An abuser of calcium channel drugs was found to be edematous with hyperplastic gingiva in physical examination.

 

Case X

Queena is having left sided congestive heart failure. Chest X-ray revealed left ventricular hypertrophy. She already had a previous myocardial infarction. As the cardiologist, you prescribed a long-acting angiotensin-converting enzyme inhibitor and active drug quinaprilat.

Fosinopril is the only drug with phosphate ligand. The rest of ACE inhibitor prodrugs have carboxyl groups.

 

Case XI

Sarah has hypertension. She does not tolerate ACE inhibitors very well so you prescribed to her the angiotensin II receptor blocker, saralasin. After her hypertension is cured, you found out that she was pregnant and you stopped her medication. She later developed glomerulonephritis due to some bacterial infection and you removed ARBs from her treatment options for hypertension. After she was cured from her kidney disease, you replaced here ARB with longer-lasting ARBs like losartan.

 

Case XII

Ranny already had myocardial infarction. You gave him ranolazine to further counter the ischemia.

 

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Antigiardiasis Durgs

In Uncategorized on September 8, 2012 at 7:57 pm

This is Giardia lamblia

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biotech-weblog.com

Nikita was diagnosed to have Giardiasis. Since no cure has worked yet, she was given nitazoxanide. Other cryptosporidia in her body also dies as well as most bacteria, roundworms, flatworms and flukes. However, she later discovered that she could only urinate with difficulty. She had flank pain and her menstruation is devoid of blood. She had nosebleed and pharyngitis. Her heartbeat shot up and syncope was found. She began experiencing muscle pain and her bones broke.

Antitrypanosomal drugs

In Uncategorized on September 8, 2012 at 7:35 pm

Edwin Flor was brought to the hospital. He was diagnosed with African Sleeping Sickness from Trypanosoma brucei gambiense which he got after a hunting trip to Sudan. He was given eflornithine but he developed thrombocytopenia. He later developed convulsions

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The Matthews Story

Nifty, a 40 year old elephant hunter from America, suddenly collapsed. You suspect Chagas disease brought by the parasite Trypanosoma cruzi. Further investigation revealed that the hotel that he stayed in Guadalajara, Mexico is infested by assassin bugs (Triatominae). His wife also went down with the disease. She was pregnant and so, you cannot use nifurtimox on the wife but you can administer it Nifty.

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Egillit’s Blog

Benz also had Chagas disease. He was given benznidazole but he had peripheral neuropathy and bone marrow depression.

Anti-Respiratory Syncytial Virus drugs

In Uncategorized on September 8, 2012 at 12:33 pm

Ribavarin could also be used for flu.

Riba’s young daughter was found to be infected by the respiratory syncytial virus manifesting in pneumonia and bronchiolitis. She was given Virazole Schering (ribavarin)

Riba, however, already had hepatitis C. She was given ribavarin with interferon (Peginterferon alpha 2a [Pagasis Roche]) which was able to cure her hepatitis C. Adefovir (Herpsera Gilead) is for Hepatitis C. She was also found to have AIDS but the onset was delayed due to the medicine. She suddenly felt dizzy and had a headache.

Her biopsy showed chronic obstructive pulmonary disease and she was also pregnant. The aerosolized-medication was halted. 

 

Anti-Influenza Drugs

In Uncategorized on September 8, 2012 at 12:17 pm

Inhibitors of Influenza Viral Uncoating

Amanda is infected with type A influenza. The doctor decided to give her amantadine (Symmetrel). This is a true virostatic agent. The hemaglutinin production in the Golgi apparatus is halted and the M2 channel is ionized. She was sent home after 12 hours of giving the medicine.

Later that day, her grandmother, Rima, was found to be sick with influenza type A, similar to Amanda’s strain. She was given amantadine but she developed seizures, nausea, vomiting, dysuria, arrythmia, pupilary dilation and psychosis. She was then given rimantadine (Flumadine Forest) and this cured her.

Inhibitors of Influenza Viral Release

Revolver Ocelot had Influenza Type B. He was given oseltamivir (Tamiflu). However, he devloped gastrointestinal adverse reactions because he had kidney problems.

Zangief also has a flu. He was given a microionized powder of Zanamivir. He also had a mild asthma-like attack during treatment. The flu duration was reduced by 1 1/2 days.

Ocelot and Zangief, through the early intervention of doctors, was not able to develop flu-associated complications like otitis media and lower respiratory tract infection (bronchopneumonia).